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Gene id |
4831 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
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Gene Symbol |
NME2 Gene UCSC Ensembl |
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Aliases |
NDKB, NDPK-B, NDPKB, NM23-H2, NM23B, PUF |
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Gene name |
NME/NM23 nucleoside diphosphate kinase 2 |
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Alternate names |
nucleoside diphosphate kinase B, HEL-S-155an, NDP kinase B, c-myc purine-binding transcription factor PUF, c-myc transcription factor, epididymis secretory sperm binding protein Li 155an, histidine protein kinase NDKB, non-metastatic cells 2, protein (NM23) expr, |
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Gene location |
17q21.33 (81860534: 81843158) Exons: 10 NC_000017.11
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Gene summary(Entrez) |
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighb
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OMIM |
156491 |
Protein Summary
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| Associated diseases |
References |
| urinary bladder cancer | PMID:7614395 |
| Prostatic hypertrophy | PMID:7693635 |
| Arteriosclerosis | PMID:17272673 |
| Ovarian cancer | PMID:8519661 |
| Teratoma | PMID:7518576 |
| ovarian carcinoma | PMID:7907945 |
| congestive heart failure | PMID:11121795 |
| Cryptorchidism | MIK: 28606200 |
| Teratozoospermia | MIK: 17327269 |
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
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Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
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Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
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Male infertility |
MeDIP-Seq
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Show abstract |
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