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Gene id 4494
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol MT1F   Gene   UCSC   Ensembl
Aliases MT1
Gene name metallothionein 1F
Alternate names metallothionein-1F, MT-1F, MT-IF, metallothionein 1F (functional), metallothionein-IF,
Gene location 16q13 (166308391: 166305299)     Exons: 1     NC_000006.12
OMIM 156352

Protein Summary

Protein general information P04733  

Name: Metallothionein 1F (MT 1F) (Metallothionein IF) (MT IF)

Length: 61  Mass: 6086

Sequence MDPNCSCAAGVSCTCAGSCKCKECKCTSCKKSCCSCCPVGCSKCAQGCVCKGASEKCSCCD
Structural information
Interpro:  IPR003019  IPR017854  IPR023587  IPR000006  IPR018064  
Prosite:   PS00203
STRING:   ENSP00000334872
Other Databases GeneCards:  MT1F  Malacards:  MT1F

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0006882 cellular zinc ion homeost
asis
IBA biological process
GO:0010273 detoxification of copper
ion
IBA biological process
GO:0046872 metal ion binding
IBA molecular function
GO:0005634 nucleus
IBA cellular component
GO:0005737 cytoplasm
IBA cellular component
GO:0071276 cellular response to cadm
ium ion
IBA biological process
GO:0071280 cellular response to copp
er ion
IBA biological process
GO:0071294 cellular response to zinc
ion
IBA biological process
GO:0046872 metal ion binding
IEA molecular function
GO:0046872 metal ion binding
IEA molecular function
GO:0046872 metal ion binding
IEA molecular function
GO:0005515 protein binding
IPI molecular function
GO:0005634 nucleus
IDA cellular component
GO:0005737 cytoplasm
IDA cellular component
GO:0045926 negative regulation of gr
owth
ISS biological process
GO:0008270 zinc ion binding
ISS molecular function
GO:0071294 cellular response to zinc
ion
ISS biological process
GO:0071276 cellular response to cadm
ium ion
IEP biological process

KEGG pathways

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Pathway idPathway name
hsa04978Mineral absorption
Associated diseases References
Aberrant CpGs in Low Motility Sperm MIK: 21674046
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia

13 (5 controls,
8 cases)
Male infertility GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract