Male Infertility Database

Search Result

Gene id

4245

Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed

Gene Summary

Gene Symbol

MGAT1 Gene UCSC Ensembl

Aliases

GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, GnTI, MGAT

Gene name

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Alternate names

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, glcNAc-T I, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase,

Gene location

5q35.3 (180815615: 180784779) Exons: 11 NC_000020.11

Gene summary(Entrez)

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme e

OMIM

160995

Protein Summary

Gene ontology

Expand All | Collapse All

GO accession	Term name	Evidence code	Go category

KEGG pathways

Expand All | Collapse All

Pathway id	Pathway name
hsa01100	Metabolic pathways
hsa00010	Glycolysis / Gluconeogenesis
hsa00020	Citrate cycle
hsa01100	Metabolic pathways
hsa00513	Various types of N-glycan biosynthesis
hsa00510	N-Glycan biosynthesis

Diseases

Expand All | Collapse All

Associated diseases	References
Obesity	GAD: 19851299
Spermatogenesis defects	MIK: 29386567
Cryptorchidism	MIK: 28606200
Spermatogenetic defects	MIK: 29386567
Male infertility	MIK: 29386567
Unexplained infertility	MIK: 25753583

PubMed references

Expand All | Collapse All

PMID	Condition	Population details	Infertility_type	Associated_genes	Abstract
29386567	Spermatoge netic defe cts, Male infertilit y		Male infertility		Show abstract
28606200	Cryptorchi dism	Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
28606200	Cryptorchi dism	Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
28606200	Cryptorchi dism	Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
25753583	Unexplaine d infertil ity	46 (17 fertile men, 29 male pa tients)	Male infertility	Microarray	Show abstract

Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

Protein Summary

Gene ontology

Expand All | Collapse All

KEGG pathways

Expand All | Collapse All

Expand All | Collapse All

Diseases

Expand All | Collapse All

Expand All | Collapse All

PubMed references

Expand All | Collapse All

Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

Protein Summary

Gene ontology

Expand All | Collapse All

KEGG pathways Expand All | Collapse All

Expand All | Collapse All

Diseases Expand All | Collapse All

Expand All | Collapse All

PubMed references

Expand All | Collapse All

KEGG pathways

Expand All | Collapse All

Diseases

Expand All | Collapse All