|
Gene id |
4184 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
SMCP Gene UCSC Ensembl |
|
Aliases |
HSMCSGEN1, MCS, MCSP |
|
Gene name |
sperm mitochondria associated cysteine rich protein |
|
Alternate names |
sperm mitochondrial-associated cysteine-rich protein, testicular tissue protein Li 119, testicular tissue protein Li 161, |
|
Gene location |
1q21.3 (152878321: 152885046) Exons: 2 NC_000017.11
|
|
Gene summary(Entrez) |
Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by
|
|
OMIM |
601148 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Asthenozoospermia | MIK: 11940662 |
| Abnormal protamine expression and male infertility | MIK: 25336347 |
| Abnormal protamine expression and male infertility | MIK: 25336347 |
| Male infertility | MIK: 25336347 |
| Asthenozoospermia | MIK: 11940662 |
| Non obstructive azoospermia | MIK: 24012201 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 11940662 |
Asthenozoo
spermia, M
ale infert
ility
|
|
|
|
Male infertility |
|
Show abstract |
| 25336347 |
Abnormal p
rotamine e
xpression
and male i
nfertility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|