Male Infertility Database

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Gene id

4128

Gene Summary SNPs Protein Summary Gene ontology KEGG pathways Diseases PubMed

Gene Summary

Gene Symbol

MAOA Gene UCSC Ensembl

Aliases

BRNRS, MAO-A

Gene name

monoamine oxidase A

Alternate names

amine oxidase [flavin-containing] A, monoamine oxidase type A,

Gene location

Xp11.3 (43654906: 43746823) Exons: 16 NC_000023.11

Gene summary(Entrez)

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has

OMIM

309850

SNPs

rs3788862

Strand:    Allele origin:   Allele change:   Mutation type: snv

NC_000023.11   g.43658116A>C
NC_000023.11   g.43658116A>G
NC_000023.10   g.43517364A>C
NC_000023.10   g.43517364A>G
NG_008957.2   g.6956A>C
NG_008957.2   g.6956A>G|SEQ=[A/C/G]|GENE=MAOA

Protein Summary

Gene ontology

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GO accession	Term name	Evidence code	Go category

KEGG pathways

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Pathway id	Pathway name
hsa01100	Metabolic pathways
hsa04728	Dopaminergic synapse
hsa04726	Serotonergic synapse
hsa05030	Cocaine addiction
hsa05031	Amphetamine addiction
hsa05034	Alcoholism

Diseases

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Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Asthenozoospermia	MIK: 29602729
Male infertility	MIK: 29602729
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

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PMID	Condition	Mutation	Population details	Infertility_type	Associated_genes	Abstract
29602729	Asthenozoo spermia, M ale infert ility	rs3788862	285 (182 normos permia, 103 ast henozoospermia)	Male infertility		Show abstract
17327269	Teratozoos permia		13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)	Show abstract
17327269	Teratozoos permia		19 (6 controls , 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)	Show abstract
17327269	Teratozoos permia		19 (6 controls , 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)	Show abstract
21674046	Aberrant C pGs in Low Motility Sperm		18	Male infertility	GSE26881	Show abstract
28606200	Cryptorchi dism		Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
31037746	Spermatoge nic defect s		16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R	Show abstract

Male Infertility knowledgebase

A repository with genes crucial for male fertility

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Gene Summary

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Diseases

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PubMed references

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Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

SNPs

Protein Summary

Gene ontology

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KEGG pathways Expand All | Collapse All

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Diseases Expand All | Collapse All

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PubMed references

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KEGG pathways

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Diseases

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