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Gene id 406948
Gene Summary    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol MIR15A   Gene   UCSC   Ensembl
Aliases MIRN15A, hsa-mir-15a, miRNA15A, mir-15a
Gene name microRNA 15a
Gene location 13q14.2 (50049200: 50049118)     Exons: 1     NC_000013.11
Gene summary(Entrez) microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
OMIM 609703

KEGG pathways

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Pathway idPathway name
hsa05206MicroRNAs in cancer
Associated diseases References
Varicocele MIK: 24481955
Non obstructive azoospermia MIK: 24012201
Sertoli cell only syndrome MIK: 23869807
Oligoasthenozoospermia MIK: 23312218
Teratozoospermia MIK: 17327269
 Varicocele-related sperm impairment MIK: 24481955
Male infertility MIK: 24481955

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
24481955  Varicocel
e-related 
sperm impa
irment, ma
le inferti
lity


Male infertility miR-15a
HSPA1B
Show abstract
24012201 Non obstru
ctive azoo
spermia

31 (4 controls,
27 cases)
Male infertility GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
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17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
23869807 Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome

20 (4 controls,
16 cases)
Male infertility GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
27424049 Oligoasthe
nozoosperm
ia

24 (12 normozoo
spermia, 12 Oli
goasthenozoospe
rmia)
Male infertility Microarray
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23312218 Oligoasthe
nozoosperm
ia

27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
Male infertility NGS
Show abstract