|
Gene id |
406938 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MIR146A Gene UCSC Ensembl |
|
Aliases |
MIRN146, MIRN146A, miR-146a, miRNA146A |
|
Gene name |
microRNA 146a |
|
Alternate names |
hsa-mir-146, hsa-mir-146a, |
|
Gene location |
5q33.3 (160485351: 160485449) Exons: 1 NC_000005.10
|
|
Gene summary(Entrez) |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
|
|
OMIM |
610566 |
|
| Pathway id | Pathway name |
|---|
| hsa05206 | MicroRNAs in cancer | |
|
| Associated diseases |
References |
| Cancer (esophageal) | GAD: 19138993 |
| Cancer (Hepatocellular) | GAD: 18711148 |
| Cancer (prostate) | GAD: 19902466 |
| Cancer | GAD: 19902466 |
| Cancer (stomach) | GAD: 20653068 |
| Cancer (ovarian) | GAD: 20810544 |
| Cancer (Squamous cell) | GAD: 20549817 |
| Cancer (Renal cell) | GAD: 20732906 |
| Cancer (breast) | GAD: 19847796 |
| Heart disease | GAD: 19514064 |
| Cardiovascular disease | GAD: 19514064 |
| Cardiovascular disease | GAD: 20488170 |
| Arthritis | GAD: 20870441 |
| Premature ovarian failure (POF) | INFBASE: 22872486 |
| Male subfertility | MIK: 25740880 |
| Asthenozoospemia | MIK: 23312218 |
| Male subfertility | MIK: 25740880 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25740880 |
Male subfe
rtility
|
|
|
179 (60 subject
s each (explora
tory and confir
matory cohort),
40 hypogonadal
, 40 eugonadal,
39 controls)
|
Male infertility |
miR-155
miR-146a
|
Show abstract |
| 23312218 |
Asthenozoo
spemia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
|