|
Gene id |
406906 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MIR122 Gene UCSC Ensembl |
|
Aliases |
MIR122A, MIRN122, MIRN122A, hsa-mir-122, miRNA122, miRNA122A, mir-122 |
|
Gene name |
microRNA 122 |
|
Alternate names |
hsa-mir-122a, microRNA 122a, |
|
Gene location |
18q21.31 (58451073: 58451157) Exons: 1 NC_000018.10
|
|
Gene summary(Entrez) |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
|
|
OMIM |
609582 |
|
| Pathway id | Pathway name |
|---|
| hsa05206 | MicroRNAs in cancer | |
|
| Associated diseases |
References |
| Endometriosis | INFBASE: 23118427 |
| Spermatogenesis defects | MIK: 26648257 |
| Non obstructive azoospermia | MIK: 25108464 |
| Asthenozoospermia | MIK: 27264812 |
| Azoospermia | MIK: 21933900 |
| Asthenozoospermia | MIK: 21933900 |
| Maturation arrest | MIK: 26648257 |
| Asthenozoospemia | MIK: 23312218 |
| Azoospermia | MIK: 21933900 |
| Cryptorchidism | MIK: 30103742 |
| Obstructive azoospermia | MIK: 30103742 |
| Male infertility | MIK: 30103742 |
| Asthenospermia | MIK: 27264812 |
| Non obstructive azoospermia | MIK: 31134916 |
| Oligoasthenozoospermia | MIK: 23312218 |
| Spermatogenic defects | MIK: 26648257 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25108464 |
Male infer
tility, no
nobstructi
ve azoospe
rmia [NOA]
|
|
|
226 men present
ing at an infer
tility clinic
|
Male infertility |
miR-34b*
miR-34b
miR-34c-5p
miR-429
miR-122
|
Show abstract |
| 27264812 |
Idiopathic
asthenosp
ermia
|
|
|
|
Male infertility |
miR-122-3p
miR-141-5p
|
Show abstract |
| 26648257 |
Spermatoge
nic failur
e, maturat
ion failur
e
|
|
|
|
Male infertility |
miR-449a
miR-34c-5p and miR-122
|
Show abstract |
| 21933900 |
Azoospermi
a, astheno
zoospermia
|
|
|
457 (289 infert
ile men (118 no
n obstructive a
zoospermia, 137
asthenozoosper
mia, 34 oligosp
ermia), 168 age
-matched fertil
e controls)
|
Male infertility |
miR-122
|
Show abstract |
| 30103742 |
Cryptorchi
dism, Obst
ructive az
oospermia,
Male infe
rtility
|
|
|
6 (3 post-crypt
orchidopexy tes
ticular tissue
samples, 3 obst
ructive azoospe
rmia)
|
Male infertility |
Microarray microRNAs
|
Show abstract |
| 23312218 |
Asthenozoo
spemia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
| 23312218 |
Oligoasthe
nozoosperm
ia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
| 23312218 |
Oligoasthe
nozoosperm
ia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
| 31134916 |
Non- obstr
uctive azo
ospermia
|
|
|
77 (39 NOA, 38
controls)
|
Male infertility |
Microarray
|
Show abstract |
|