|
Gene id |
406885 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MIRLET7C Gene UCSC Ensembl |
|
Aliases |
LET7C, MIRNLET7C, hsa-let-7c, let-7c |
|
Gene name |
microRNA let-7c |
|
Gene location |
21q21.1 (16539827: 16539910) Exons: 6 NC_000021.9
|
|
Gene summary(Entrez) |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
|
|
OMIM |
612144 |
|
| Pathway id | Pathway name |
|---|
| hsa05206 | MicroRNAs in cancer | |
|
| Associated diseases |
References |
| hepatocellular carcinoma | PMID:22289550 |
| Non obstructive azoospermia | MIK: 24012201 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Oligoasthenozoospermia | MIK: 23312218 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 24012201 |
Non obstru
ctive azoo
spermia
|
|
|
31 (4 controls,
27 cases)
|
Male infertility |
GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23312218 |
Oligoasthe
nozoosperm
ia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
|