|
Gene id |
406884 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MIRLET7B Gene UCSC Ensembl |
|
Aliases |
LET7B, MIRNLET7B, hsa-let-7b, let-7b |
|
Gene name |
microRNA let-7b |
|
Gene location |
22q13.31 (46113685: 46113767) Exons: 1 NC_000022.11
|
|
Gene summary(Entrez) |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
|
|
OMIM |
611249 |
|
| Pathway id | Pathway name |
|---|
| hsa05206 | MicroRNAs in cancer | |
|
| Associated diseases |
References |
| Endometriosis | INFBASE: 25772772 |
| Asthenozoospermia | MIK: 26626315 |
| Asthenozoospermia | MIK: 29653228 |
| Male infertility | MIK: 29653228 |
| Cryptorchidism | MIK: 28606200 |
| Hypospadias | MIK: 30565690 |
| Oligoasthenozoospermia | MIK: 23312218 |
| Spermatogenic failure | MIK: 22735917 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 26626315 |
Asthenozoo
spermia
|
|
|
|
Male infertility |
miR-101-3p
miR-151a-5p
let-7b-5p
|
Show abstract |
| 29653228 |
Asthenozoo
spermia, M
ale infert
ility
|
|
|
|
Male infertility |
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 23312218 |
Oligoasthe
nozoosperm
ia
|
|
|
27 (9 normozoos
permia, 9 oligo
asthenozoosperm
ia, 9 asthenozo
ospermia)
|
Male infertility |
NGS
|
Show abstract |
| 30565690 |
Hypospadia
s
|
|
|
|
Male infertility |
Microarray
|
Show abstract |
| 22735917 |
Spermatoge
nic failur
e
|
|
|
69 samples
|
Male infertility |
Microarray
|
Show abstract |
|