|
Gene id |
406881 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
MIRLET7A1 Gene UCSC Ensembl |
|
Aliases |
LET7A1, MIRNLET7A1, let-7a-1 |
|
Gene name |
microRNA let-7a-1 |
|
Alternate names |
hsa-let-7a-1, |
|
Gene location |
9q22.32 (94175956: 94176035) Exons: 1 NC_000009.12
|
|
Gene summary(Entrez) |
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I
|
|
OMIM |
605386 |
|
| Pathway id | Pathway name |
|---|
| hsa05206 | MicroRNAs in cancer | |
|
| Associated diseases |
References |
| Cancer (ovarian) | GAD: 20167074 |
| Endometriosis | INFBASE: 22307873 |
| Male factor infertility | MIK: 22675043 |
| Spermatogenesis defects | MIK: 22675043 |
| Spermatogenic defects | MIK: 22675043 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 22675043 |
Spermatoge
nic failur
e
|
|
|
144 (96 idiopat
hic infertile m
ales (48 oligoz
oospermia and 4
8 NOA), 48 fert
ile controls)
|
Male infertility |
miR-19b
let-7a
|
Show abstract |
|