• Gene id: 400566

Gene Summary

• Gene Symbol: C17orf97   Gene   UCSC   Ensembl
• Aliases: CK20, LIAT1
• Gene name: chromosome 17 open reading frame 97
• Alternate names: protein LIAT1, ligand of ATE1 protein,
• Gene location: 17p13.3 (410324: 414665)     Exons: 4     NC_000017.11

Protein Summary

• Protein general information: Q6ZQX7  
  • Name: Protein LIAT1 (Ligand of ATE1 protein)
  • Length: 453  
  • Mass: 49656
• Sequence:

  METRGPGLAVRAESRRLVGIGPRAPPGRVGLQPSGRLDRRGGAGTMGYKDNDGEEEEREGGAAGPRGSRLPPITG
  GASELAKRKVKKKKRKKKTKGSGKGDDKHQSQSLKSQPLSSSFHDILSPCKERGPKPEHRQSKVEKKHLPSDSST
  VSLPDFAEIENLANRINESLRWDGILADPEAEKERIRIYKLNRRKRYRCLALKGFHPDPEALKGFHPDPDALKGF
  HPDPEALKGFHPDPEALKGFHPDPEALKGFHPDPEALKGIHPDPEALKGIHPDPEALKGFHPDPEALKGFHPDPE
  ALKGFHTDPEALKGFHIDPEALKGFHPDPKALKGFHPDPKALKGFHTDPEALKGFHPDPKALKGFHPDPEALKGF
  HPDPEALKGFHPDPEALKGFHTDPNAEEAPENLPYLSDKDGSSSHRQPTSKAECPNLCFEGNLTPKLLHSDLAPT
  LLE

• Structural information:
  • Interpro: IPR038794  
  • STRING: ENSP00000353245
• Other Databases: GeneCards:  C17orf97  Malacards:  C17orf97

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016598	protein arginylation	IBA	biological process
GO:0016598	protein arginylation	ISS	biological process
GO:0016598	protein arginylation	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Non obstructive azoospermia	MIK: 24012201
Sertoli cell only syndrome	MIK: 23869807
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq