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Gene id 3956
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol LGALS1   Gene   UCSC   Ensembl
Aliases GAL1, GBP
Gene name galectin 1
Alternate names galectin-1, 14 kDa laminin-binding protein, 14 kDa lectin, HBL, HLBP14, HPL, S-Lac lectin 1, beta-galactoside-binding lectin L-14-I, beta-galactoside-binding protein 14kDa, epididymis secretory sperm binding protein, gal-1, galaptin, lactose-binding lectin 1, lectin,,
Gene location 22q13.1 (37675635: 37679801)     Exons: 4     NC_000022.11
Gene summary(Entrez) The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2
OMIM 150570

Protein Summary

Gene ontology

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GO accessionTerm nameEvidence codeGo category
Associated diseases References
Cancer GAD: 19730683
Endometriosis INFBASE: 25473847
Aberrant CpGs in Low Motility Sperm MIK: 21674046
Regulating sperm motility and membrane hyperpolarization MIK: 26136479
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
26136479 Regulating
sperm mot
ility and
membrane h
yperpolari
zation


Male infertility
Show abstract
17327269 Teratozoos
permia

13 (5 controls,
8 cases)
Male infertility GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract