• Gene id: 391712

Gene Summary

• Gene Symbol: TRIM61   Gene   UCSC   Ensembl
• Aliases: RNF35
• Gene name: tripartite motif containing 61
• Alternate names: putative tripartite motif-containing protein 61, ring finger protein 35,
• Gene location: 4q32.3 (164977656: 164954445)     Exons: 5     NC_000004.12

Protein Summary

• Protein general information: Q5EBN2  
  • Name: Putative tripartite motif containing protein 61 (RING finger protein 35)
  • Length: 209  
  • Mass: 24047
• Sequence:

  MEFVTALADLRAEASCPICLDYLKDPVTISCGHNFCLSCIIMSWKDLHDSFPCPFCHFCCPERKFISNPQLGSLT
  EIAKQLQIRSKKRKRQEEKHVCKKHNQVLTFFCQKDLELLCPRCSLSTDHQHHCVWPIKKAASYHRKKLEEYNAP
  WKERVELIEKVITMQTRKSLELKKKMESPSVTRLECSCTISAHFNLRLPGSSDSSASGS

• Structural information:
  • Interpro: IPR000315  IPR001841  IPR013083  IPR017907  
  • Prosite: PS50119 PS00518 PS50089
  • STRING: ENSP00000332288
• Other Databases: GeneCards:  TRIM61  Malacards:  TRIM61

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0061630	ubiquitin protein ligase activity	IBA	molecular function
GO:0016567	protein ubiquitination	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component
GO:0008270	zinc ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq