• Gene id: 390928

Gene Summary

• Gene Symbol: ACP7   Gene   UCSC   Ensembl
• Aliases: PAPL, PAPL1
• Gene name: acid phosphatase 7, tartrate resistant (putative)
• Alternate names: acid phosphatase type 7, iron/zinc purple acid phosphatase-like protein, purple acid phosphatase long form 1,
• Gene location: 19q13.2 (39083010: 39112073)     Exons: 14     NC_000019.10
• Gene summary(Entrez): Purple acid phosphatases (PAPs), including PAPL, are a family of binuclear metallohydrolases that have been identified in plants, animals, and fungi (Flanagan et al., 2006 [PubMed 16793224]).[supplied by OMIM, Mar 2008]

Protein Summary

• Protein general information: Q6ZNF0  
  • Name: Acid phosphatase type 7 (EC 3.1.3.2) (Purple acid phosphatase long form)
  • Length: 438  
  • Mass: 50480
• Sequence:

  MHPLPGYWSCYCLLLLFSLGVQGSLGAPSAAPEQVHLSYPGEPGSMTVTWTTWVPTRSEVQFGLQPSGPLPLRAQ
  GTFVPFVDGGILRRKLYIHRVTLRKLLPGVQYVYRCGSAQGWSRRFRFRALKNGAHWSPRLAVFGDLGADNPKAV
  PRLRRDTQQGMYDAVLHVGDFAYNLDQDNARVGDRFMRLIEPVAASLPYMTCPGNHEERYNFSNYKARFSMPGDN
  EGLWYSWDLGPAHIISFSTEVYFFLHYGRHLVQRQFRWLESDLQKANKNRAARPWIITMGHRPMYCSNADLDDCT
  RHESKVRKGLQGKLYGLEDLFYKYGVDLQLWAHEHSYERLWPIYNYQVFNGSREMPYTNPRGPVHIITGSAGCEE
  RLTPFAVFPRPWSAVRVKEYGYTRLHILNGTHIHIQQVSDDQDGKIVDDVWVVRPLFGRRMYL

• Structural information:
  • Interpro: IPR004843  IPR029052  IPR041792  IPR008963  IPR015914   IPR025733  
  • CDD: cd00839
  • STRING: ENSP00000327557
• Other Databases: GeneCards:  ACP7  Malacards:  ACP7

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003993	acid phosphatase activity	IEA	molecular function
GO:0016787	hydrolase activity	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0016787	hydrolase activity	IEA	molecular function
GO:0005576	extracellular region	IEA	cellular component
GO:0003993	acid phosphatase activity	IEA	molecular function
GO:0005576	extracellular region	IEA	cellular component
GO:0016311	dephosphorylation	IEA	biological process
GO:0016311	dephosphorylation	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq