• Gene id: 389362

Gene Summary

• Gene Symbol: PSMG4   Gene   UCSC   Ensembl
• Aliases: C6orf86, PAC4, bA506K6.2
• Gene name: proteasome assembly chaperone 4
• Alternate names: proteasome assembly chaperone 4, PAC-4, hPAC4, proteasome (prosome, macropain) assembly chaperone 4,
• Gene location: 6p25.2 (3254324: 3308223)     Exons: 6     NC_000006.12
• OMIM: 617550

Protein Summary

• Protein general information: Q5JS54  
  • Name: Proteasome assembly chaperone 4 (PAC 4) (hPAC4)
  • Length: 123  
  • Mass: 13775
• Sequence:

  MEGLVVAAGGDVSLHNFSARLWEQLVHFHVMRLTDSLFLWVGATPHLRNLAVAMCSRYDSIPVSTSLLGDTSDTT
  STGLAQRLARKTNKQVFVSYNLQNTDSNFALLVENRIKEEMEAFPEKF

• Structural information:
  • Interpro: IPR032157  
  • PDB: 5WTQ
  • PDBsum: 5WTQ
• Other Databases: GeneCards:  PSMG4  Malacards:  PSMG4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0043248	proteasome assembly	IEA	biological process
GO:0032991	protein-containing complex	IEA	cellular component
GO:0044877	protein-containing complex binding	IEA	molecular function
GO:0044877	protein-containing complex binding	ISS	molecular function
GO:0032991	protein-containing complex	ISS	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)