• Gene id: 388333

Gene Summary

• Gene Symbol: SPDYE4   Gene   UCSC   Ensembl
• Gene name: speedy/RINGO cell cycle regulator family member E4
• Alternate names: speedy protein E4, putative Speedy protein E4, speedy homolog E4,
• Gene location: 17p13.1 (8759427: 8747531)     Exons: 7     NC_000017.11
• OMIM: 617628

Protein Summary

• Protein general information: A6NLX3  
  • Name: Speedy protein E4
  • Length: 237  
  • Mass: 27806
• Sequence:

  MASGQARPPFEEESPQPSTTVRSPEVVVDDEVPGPSAPWIDPSPQPQSLGLKRKSEWSDESEEELEEELELERAP
  EPEDTWVVETLCGLKMKLKRKRASSVLPEHHEAFNRLLGDPVVQKFLAWDKDLRVSDKYLLAMVIAYFSRAGLFS
  WQYQRIHFFLALYLASDMEEDNQAPKQDIFSFLYGKNYSQRPLFHKLRYQLLCSMRWRTWVSPEEMEEIQAYDPE
  HWVWARDRTLIS

• Structural information:
  • Interpro: IPR020984  
  • STRING: ENSP00000329522
• Other Databases: GeneCards:  SPDYE4  Malacards:  SPDYE4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0019901	protein kinase binding	IBA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

KEGG pathways

Pathway id	Pathway name
hsa04114	Oocyte meiosis
hsa04914	Progesterone-mediated oocyte maturation

Diseases

Associated diseases	References
Non obstructive azoospermia	MIK: 24012201

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)