• Gene id: 387694

Gene Summary

• Gene Symbol: SH2D4B   Gene   UCSC   Ensembl
• Gene name: SH2 domain containing 4B
• Alternate names: SH2 domain-containing protein 4B, novel SH2 domain-containing protein,
• Gene location: 10q23.1 (80537901: 80646559)     Exons: 7     NC_000010.11
• OMIM: 616438

Protein Summary

• Protein general information: Q5SQS7  
  • Name: SH2 domain containing protein 4B
  • Length: 431  
  • Mass: 51232
• Sequence:

  MLQQILHDMYIDPELLAELSDVQKHILFYKMREEQLRRWKERETWEALAQDEGLRPPKTKRASDKHIQWLLGADG
  EVWVWIMGEGPGDKPYEEISEELIAERARLQAQREAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRK
  AAKVLEERIHEEFKRKEEEERKRGEEQIRLQEEQRAKELYWTLKQAQLHCQASEKEEREWEEQLRRSKAADEERS
  RRAQRARDEYRHHSLRAIQKGTVAGLSSMFRELGQSHEQEARLYHHLPDPGLPQPLALPVRTWERPLRPVSRDVI
  VRWFKEEQLPRRAGFERNTKFIAPWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTLSYRLQKGFKHFLVDA
  SGDFYSFLGVDPNRHATLTDLVDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE

• Structural information:
  • Protein Domains: (325..41-)
    (/note="SH2-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00191"-)
  • Interpro: IPR000980  IPR036860  IPR035839  
  • Prosite: PS50001
  • CDD: cd10351
  • STRING: ENSP00000345295
• Other Databases: GeneCards:  SH2D4B  Malacards:  SH2D4B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq