• Gene id: 375743

Gene Summary

• Gene Symbol: PTAR1   Gene   UCSC   Ensembl
• Gene name: protein prenyltransferase alpha subunit repeat containing 1
• Alternate names: protein prenyltransferase alpha subunit repeat-containing protein 1,
• Gene location: 9q21.12 (69760043: 69709524)     Exons: 9     NC_000009.12
• OMIM: 0

Protein Summary

• Protein general information: Q7Z6K3  
  • Name: Protein prenyltransferase alpha subunit repeat containing protein 1
  • Length: 402  
  • Mass: 46405
• Sequence:

  MAETSEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLY
  RTRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQL
  IQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKH
  WASMHVSDHSGFHYRQFLLKSLISQTVIDSSVMEQNPLRSEPALVPPKDEEAAVSTEEPRINLPHLLEEEVEFST
  DLIDSYPGHETLWCHRRHIFYLQHHLNAGSQLSQAMEVDGLNDSSKQGYSQETKRLKRTPVPDSLGLEMEHRFID
  QVLSTCRNVEQARFASAYRKWLVTLSQ

• Structural information:
  • Interpro: IPR002088  
  • Prosite: PS51147
  • PDB: 6J6X 6J74 6J7F 6J7X 6O60
  • PDBsum: 6J6X 6J74 6J7F 6J7X 6O60
  • STRING: ENSP00000344299
• Other Databases: GeneCards:  PTAR1  Malacards:  PTAR1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0018342	protein prenylation	IBA	biological process
GO:0018342	protein prenylation	IEA	biological process
GO:0008318	protein prenyltransferase activity	IEA	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0004659	prenyltransferase activity	IEA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)