• Gene id: 346689

Gene Summary

• Gene Symbol: KLRG2   Gene   UCSC   Ensembl
• Aliases: CLEC15B
• Gene name: killer cell lectin like receptor G2
• Alternate names: killer cell lectin-like receptor subfamily G member 2, C-type lectin domain family 15 member B, killer cell lectin-like receptor subfamily G, member 2,
• Gene location: 7q34 (139483715: 139426930)     Exons: 7     NC_000007.14

Protein Summary

• Protein general information: A4D1S0  
  • Name: Killer cell lectin like receptor subfamily G member 2 (C type lectin domain family 15 member B)
  • Length: 409  
  • Mass: 42851
• Sequence:

  MEESWEAAPGGQAGAELPMEPVGSLVPTLEQPQVPAKVRQPEGPESSPSPAGAVEKAAGAGLEPSSKKKPPSPRP
  GSPRVPPLSLGYGVCPEPPSPGPALVKLPRNGEAPGAEPAPSAWAPMELQVDVRVKPVGAAGGSSTPSPRPSTRF
  LKVPVPESPAFSRHADPAHQLLLRAPSQGGTWGRRSPLAAARTESGCDAEGRASPAEGSAGSPGSPTCCRCKELG
  LEKEDAALLPRAGLDGDEKLPRAVTLTGLPMYVKSLYWALAFMAVLLAVSGVVIVVLASRAGARCQQCPPGWVLS
  EEHCYYFSAEAQAWEASQAFCSAYHATLPLLSHTQDFLGRYPVSRHSWVGAWRGPQGWHWIDEAPLPPQLLPEDG
  EDNLDINCGALEEGTLVAANCSTPRPWVCAKGTQ

• Structural information:
  • Protein Domains: (300..40-)
    (/note="C-type-lectin)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00040"-)
  • Interpro: IPR001304  IPR016186  IPR016187  IPR033992  
  • Prosite: PS50041
  • CDD: cd03593
  • STRING: ENSP00000339356
• Other Databases: GeneCards:  KLRG2  Malacards:  KLRG2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0030246	carbohydrate binding	IEA	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881