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Gene id 3439
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol IFNA1   Gene   UCSC   Ensembl
Aliases IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@
Gene name interferon alpha 1
Alternate names interferon alpha-1/13, IFN-alpha 1b, IFN-alpha-1/13, interferon alpha 1b, interferon alpha-D, interferon-alpha1, leIF D,
Gene location 9p21.3 (21440453: 21441315)     Exons: 1     NC_000009.12
Gene summary(Entrez) The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011]
OMIM 147660

Protein Summary

Gene ontology

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GO accessionTerm nameEvidence codeGo category

KEGG pathways

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Pathway idPathway name
hsa04151PI3K-Akt signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04217Necroptosis
hsa04620Toll-like receptor signaling pathway
hsa04621NOD-like receptor signaling pathway
hsa04622RIG-I-like receptor signaling pathway
hsa04623Cytosolic DNA-sensing pathway
hsa04650Natural killer cell mediated cytotoxicity
hsa05200Pathways in cancer
hsa05320Autoimmune thyroid disease
hsa05152Tuberculosis
hsa05170Human immunodeficiency virus 1 infection
hsa05162Measles
hsa05164Influenza A
hsa05161Hepatitis B
hsa05160Hepatitis C
hsa05168Herpes simplex virus 1 infection
hsa05163Human cytomegalovirus infection
hsa05167Kaposi sarcoma-associated herpesvirus infection
hsa05169Epstein-Barr virus infection
hsa05165Human papillomavirus infection
Associated diseases References
Cancer GAD: 18633131
Cancer (melanoma) GAD: 20574843
Cancer (leukemia) GAD: 20959405
Cancer (lymphoma) GAD: 18633131
Irritable bowel syndrome GAD: 20860222
Arthritis GAD: 11315919
Behcet's disease GAD: 19796549
Behcet's disease GAD: 19796549
Systemic lupus erythematosus (SLE) GAD: 19000144
Arthritis GAD: 11315919
Male factor infertility MIK: 11476770
Azoospermia MIK: 9583358
Male factor infertility MIK: 9583358
Oligozoospermia MIK: 9583358
Male factor infertility MIK: 11476770
Oligozoospermia MIK: 9583358
Azoospermia MIK: 9583358

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
11476770 Male facto
r infertil
ity

9 sperm donors
Male infertility TYK 2
STAT 1
IFN-alpha
IFN-gamma
IL-12
TYK 2
STAT 4
Show abstract
9583358 Oligozoosp
ermia, Azo
ospermia

101 (31 normozo
ospermic, 57 ol
igozoospermic,
13 azoospermic
men)
Male infertility interferon alpha
Show abstract