• Gene id: 342898

Gene Summary

• Gene Symbol: SYCN   Gene   UCSC   Ensembl
• Aliases: INSSA1, SYL
• Gene name: syncollin
• Alternate names: syncollin, insulin synthesis associated 1, insulin synthesis-associated protein 1,
• Gene location: 19q13.2 (39204262: 39202824)     Exons: 2     NC_000019.10

Protein Summary

• Protein general information: Q0VAF6  
  • Name: Syncollin (Insulin synthesis associated protein 1)
  • Length: 134  
  • Mass: 14405
• Sequence:

  MSPLRPLLLALALASVPCAQGACPASADLKHSDGTRTCAKLYDKSDPYYENCCGGAELSLESGADLPYLPSNWAN
  TASSLVVAPRCELTVWSRQGKAGKTHKFSAGTYPRLEEYRRGILGDWSNAISALYCRCS

• Structural information:
  • Interpro: IPR028137  
  • STRING: ENSP00000325564
• Other Databases: GeneCards:  SYCN  Malacards:  SYCN

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0030667	secretory granule membrane	IBA	cellular component
GO:0006887	exocytosis	IEA	biological process
GO:0030667	secretory granule membrane	IEA	cellular component
GO:0031410	cytoplasmic vesicle	IEA	cellular component
GO:0006887	exocytosis	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0030667	secretory granule membrane	IEA	cellular component
GO:0030658	transport vesicle membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)