• Gene id: 339804

Gene Summary

• Gene Symbol: C2orf74   Gene   UCSC   Ensembl
• Gene name: chromosome 2 open reading frame 74
• Alternate names: uncharacterized protein C2orf74,
• Gene location: 2p15 (39425232: 39371673)     Exons: 15     NC_000005.10

Protein Summary

• Protein general information: A8MZ97  
  • Name: Uncharacterized protein C2orf74
  • Length: 194  
  • Mass: 21915
• Sequence:

  MSLLAKPMSFETTAITFFIILLICLICILLLLVVFLYKCFQGRKGKETKKVPCTDANGGVDCAAAKVVTSNPEDH
  ERILMQVMNLNVPMRPGILVQRQSKEVLATPLENRRDMEAEEENQINEKQEPENAGETGQEEDDGLQKIHTSVTR
  TPSVVESQKRPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK

• Structural information:
  • Interpro: IPR027813  
  • STRING: ENSP00000402915
• Other Databases: GeneCards:  C2orf74  Malacards:  C2orf74

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq