|
Gene id |
3010 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
H1-6 Gene UCSC Ensembl |
|
Aliases |
H1.6, H1FT, H1t, HIST1H1T, dJ221C16.2 |
|
Gene name |
H1.6 linker histone, cluster member |
|
Alternate names |
histone H1t, H1 histone family, member T (testis-specific), histone 1, H1t, histone cluster 1 H1 family member t, histone cluster 1, H1t, testicular H1 histone, |
|
Gene location |
6p22.2 (26108135: 26107411) Exons: 1 NC_000007.14
|
|
Gene summary(Entrez) |
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in
|
|
OMIM |
142712 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Leukemia | GAD: 19806355 |
| Spontaneous abortion | INFBASE: 20587610 |
| Spermatogenesis defects | MIK: 8877387 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Role in spermatogenesis | MIK: 18459115 |
| Role in spermatogenesis | MIK: 8877387 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 18459115 |
Role in sp
ermatogene
sis
|
|
|
|
Male infertility |
|
Show abstract |
| 8877387 |
Role in sp
ermatogene
sis
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|