• Gene id: 29950

Gene Summary

• Gene Symbol: SERTAD1   Gene   UCSC   Ensembl
• Aliases: SEI1, TRIP-Br1, TRIPBR1
• Gene name: SERTA domain containing 1
• Alternate names: SERTA domain-containing protein 1, CDK4-binding protein p34SEI, CDK4-binding protein p34SEI1, SEI-1, p34(SEI-1), transcriptional regulator interacting with the PHD-bromodomain 1,
• Gene location: 19q13.2 (40425991: 40421588)     Exons: 2     NC_000019.10
• OMIM: 604606

Protein Summary

• Protein general information: Q9UHV2  
  • Name: SERTA domain containing protein 1 (CDK4 binding protein p34SEI1) (SEI 1) (p34(SEI 1)) (Transcriptional regulator interacting with the PHD bromodomain 1) (TRIP Br1)
  • Length: 236  
  • Mass: 24704
• Sequence:

  MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSVLKLHHSLQQSEPDLRHLVLVVNTLR
  RIQASMAPAAALPPVPSPPAAPSVADNLLASSDAALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGAAP
  SLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDNELWAPASEGLKPGPEDGPGKEEAPELDEAELDYLMDVLVGT
  QALERPPGPGR

• Structural information:
  • Protein Domains: (38..8-)
    (/note="SERTA-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00396"-)
  • Interpro: IPR009263  
  • Prosite: PS51053
  • STRING: ENSP00000350633
• Other Databases: GeneCards:  SERTAD1  Malacards:  SERTAD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0048096	chromatin-mediated maintenance of transcription	IBA	biological process
GO:0005634	nucleus	IBA	cellular component
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	TAS	biological process
GO:0008284	positive regulation of cell population proliferation	TAS	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0045893	positive regulation of transcription, DNA-templated	IEA	biological process
GO:0045944	positive regulation of transcription by RNA polymerase II	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq