• Gene id: 28971

Gene Summary

• Gene Symbol: AAMDC   Gene   UCSC   Ensembl
• Aliases: C11orf67, CK067, PTD015
• Gene name: adipogenesis associated Mth938 domain containing
• Alternate names: mth938 domain-containing protein, UPF0366 protein C11orf67, adipogenesis associated Mth938 domain-containing protein,
• Gene location: 11q14.1 (77821113: 77901280)     Exons: 11     NC_000011.10

Protein Summary

• Protein general information: Q9H7C9  
  • Name: Mth938 domain containing protein (Adipogenesis associated Mth938 domain containing protein)
  • Length: 122  
  • Mass: 13332
• Sequence:

  MTSPEIASLSWGQMKVKGSNTTYKDCKVWPGGSRTWDWRETGTEHSPGVQPADVKEVVEKGVQTLVIGRGMSEAL
  KVPSSTVEYLKKHGIDVRVLQTEQAVKEYNALVAQGVRVGGVFHSTC

• Structural information:
  • Interpro: IPR034096  IPR036748  IPR007523  
  • CDD: cd05126
  • PDB: 2AB1 2Q4Q
  • PDBsum: 2AB1 2Q4Q
  • STRING: ENSP00000431808
• Other Databases: GeneCards:  AAMDC  Malacards:  AAMDC

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0045600	positive regulation of fat cell differentiation	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component
GO:0005737	cytoplasm	ISS	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq