• Gene id: 286006

Gene Summary

• Gene Symbol: LSMEM1   Gene   UCSC   Ensembl
• Aliases: C7orf53
• Gene name: leucine rich single-pass membrane protein 1
• Alternate names: leucine-rich single-pass membrane protein 1,
• Gene location: 7q31.1 (112479541: 112491061)     Exons: 4     NC_000007.14

Protein Summary

• Protein general information: Q8N8F7  
  • Name: Leucine rich single pass membrane protein 1
  • Length: 131  
  • Mass: 14462
• Sequence:

  MTHSSQDTGSCGIQEDGKLYVVDSINDLNKLNLCPAGSQHLFPLEDKIPVLGTNSGNGSRSLFFVGLLIVLIVSL
  ALVFFVIFLIVQTGNKMDDVSRRLTAEGKDIDDLKRINNMIVKRLNQLNQLDSEQN

• Structural information:
  • Interpro: IPR028099  
  • STRING: ENSP00000323304
• Other Databases: GeneCards:  LSMEM1  Malacards:  LSMEM1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0005829	cytosol	IDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)