• Gene id: 284613

Gene Summary

• Gene Symbol: CYB561D1   Gene   UCSC   Ensembl
• Gene name: cytochrome b561 family member D1
• Alternate names: cytochrome b561 domain-containing protein 1, cytochrome b-561 domain containing 1,
• Gene location: 1p13.3 (122882527: 122963861)     Exons: 10     NC_000011.10

Protein Summary

• Protein general information: Q8N8Q1  
  • Name: Cytochrome b561 domain containing protein 1
  • Length: 229  
  • Mass: 25424
• Sequence:

  MQPLEVGLVPAPAGEPRLTRWLRRGSGILAHLVALGFTIFLTALSRPGTSLFSWHPVFMALAFCLCMAEAILLFS
  PEHSLFFFCSRKARIRLHWAGQTLAILCAALGLGFIISSRTRSELPHLVSWHSWVGALTLLATAVQALCGLCLLC
  PRAARVSRVARLKLYHLTCGLVVYLMATVTVLLGMYSVWFQAQIKGAAWYLCLALPVYPALVIMHQISRSYLPRK
  KMEM

• Structural information:
  • Protein Domains: (22..22-)
    (/note="Cytochrome-b561)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00242"-)
  • Interpro: IPR006593  
  • Prosite: PS50939
• Other Databases: GeneCards:  CYB561D1  Malacards:  CYB561D1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016491	oxidoreductase activity	IBA	molecular function
GO:0020037	heme binding	IBA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0055114	oxidation-reduction process	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881