|
Gene id |
284217 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
LAMA1 Gene UCSC Ensembl |
|
Aliases |
LAMA, PTBHS, S-LAM-alpha |
|
Gene name |
laminin subunit alpha 1 |
|
Alternate names |
laminin subunit alpha-1, S-LAM alpha, S-laminin subunit alpha, laminin A chain, laminin, alpha 1, laminin-3 subunit alpha, |
|
Gene location |
18p11.31 (7117796: 6941741) Exons: 63 NC_000018.10
|
|
Gene summary(Entrez) |
This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the ba
|
|
OMIM |
150320 |
|
| Associated diseases |
References |
| Cancer | GAD: 20876614 |
| Asthma | GAD: 11022011 |
| Endometriosis | INFBASE: 24813083 |
| Endometriosis | INFBASE: 21658322 |
| Female infertility | INFBASE: 21658322 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Teratozoospermia | MIK: 8270377 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 8270377 |
Teratozoos
permia
|
|
|
|
Male infertility |
VLA alpha 4
VLA alpha 5 and laminin
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 17804866 |
Azoospermi
a, maturat
ion arrest
(MA), Ser
toli cell-
only syndr
ome (SCO)
|
|
|
33 (9 patients
with obstructiv
e azoospermia (
OA), 9 patients
with maturatio
n arrest (MA),
and 15 patients
with Sertoli c
ell-only syndro
me (SCO))
|
Male infertility |
|
Show abstract |
| 17187158 |
Male infer
tility, ol
igoastheno
zoospermia
, non-obst
ructive az
oospermia
(NOA), obs
tructive a
zoospermia
(OA), con
genital bi
lateral ab
sent vas d
eferens (C
BAVD)
|
|
|
125 recruited m
en were equally
divided into f
ive groups acco
rding to their
sperm concentra
tion and clinic
al examination:
fertile normoz
oospermia, olig
oasthenozoosper
mia, non-obstru
ctive azoosperm
ia (NOA), obstr
uctive azoosper
mia (OA) and co
ngenital bilate
|
Male infertility |
laminin
|
Show abstract |
|