• Gene id: 284013

Gene Summary

• Gene Symbol: VMO1   Gene   UCSC   Ensembl
• Aliases: ERGA6350, PRO21055
• Gene name: vitelline membrane outer layer 1 homolog
• Alternate names: vitelline membrane outer layer protein 1 homolog,
• Gene location: 17p13.2 (114404777: 114280759)     Exons: 24     NC_000010.11

Protein Summary

• Protein general information: Q7Z5L0  
  • Name: Vitelline membrane outer layer protein 1 homolog
  • Length: 202  
  • Mass: 21534
• Sequence:

  MERGAGAKLLPLLLLLRATGFTCAQTDGRNGYTAVIEVTSGGPWGDWAWPEMCPDGFFASGFSLKVEPPQGIPGD
  DTALNGIRLHCARGNVLGNTHVVESQSGSWGEWSEPLWCRGGAYLVAFSLRVEAPTTLGDNTAANNVRFRCSDGE
  ELQGPGLSWGDFGDWSDHCPKGACGLQTKIQGPRGLGDDTALNDARLFCCRS

• Structural information:
  • Interpro: IPR005515  IPR036706  
  • CDD: cd00220
  • STRING: ENSP00000328397
• Other Databases: GeneCards:  VMO1  Malacards:  VMO1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0003674	molecular_function	ND	molecular function
GO:0070062	extracellular exosome	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component
GO:0008150	biological_process	ND	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881