• Gene id: 283987

Gene Summary

• Gene Symbol: HID1   Gene   UCSC   Ensembl
• Aliases: 17orf28, C17orf28, DMC1, HID-1
• Gene name: HID1 domain containing
• Alternate names: protein HID1, HID1 domain-containing protein, UPF0663 transmembrane protein C17orf28, down-regulated in multiple cancers 1, downregulated in multiple cancer 1, protein hid-1 homolog,
• Gene location: 17q25.1 (74972762: 74950741)     Exons: 19     NC_000017.11

Protein Summary

• Protein general information: Q8IV36  
  • Name: Protein HID1 (Down regulated in multiple cancers 1) (HID1 domain containing protein) (Protein hid 1 homolog)
  • Length: 788  
  • Mass: 88745
  • Tissue specificity: Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric
• Sequence:

  MGSTDSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVE
  KLVQGAESGCHSEKEKQIVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEDDEHARPLAESLLLAIA
  DLLFCPDFTVQSHRRSTVDSAEDVHSLDSCEYIWEAGVGFAHSPQPNYIHDMNRMELLKLLLTCFSEAMYLPPAP
  ESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSASSA
  SPTVDGTTTGTAMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLF
  WKLCDFNKKFLFFVLKSSDVLDILVPILFFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSIRVPMD
  IPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSAAQN
  HHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRSIFHQLANLPTDPPTIHKALQRRRRTPEPLSRTGSQEGTSME
  GSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPEPQQSLEDGSPAKGEPSQAWREQRRPSTSSAS
  GQWSPTPEWVLSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQAN
  SGTAMWFRTYMWGVIYLRNVDPPVWYDTDVKLFEIQRV

• Structural information:
  • Interpro: IPR026705  
  • STRING: ENSP00000413520
• Other Databases: GeneCards:  HID1  Malacards:  HID1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000138	Golgi trans cisterna	IBA	cellular component
GO:0005797	Golgi medial cisterna	IBA	cellular component
GO:0016020	membrane	IBA	cellular component
GO:0090498	extrinsic component of Golgi membrane	IDA	cellular component
GO:0005881	cytoplasmic microtubule	IDA	cellular component
GO:0005797	Golgi medial cisterna	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0000138	Golgi trans cisterna	IDA	cellular component
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0000139	Golgi membrane	IEA	cellular component
GO:0005794	Golgi apparatus	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq