Male Infertility Database

Search Result

Gene id

282973

Gene Summary Protein Summary Gene ontology Diseases PubMed

Gene Summary

Gene Symbol

JAKMIP3 Gene UCSC Ensembl

Aliases

C10orf14, C10orf39, Jamip3, NECC2, bA140A10.5

Gene name

Janus kinase and microtubule interacting protein 3

Alternate names

janus kinase and microtubule-interacting protein 3, neuroendocrine long coiled-coil 2, neuroendocrine long coiled-coil protein 2,

Gene location

10q26.3 (132036067: 132184857) Exons: 28 NC_000010.11

OMIM

611198

Protein Summary

Protein general information

Q5VZ66

Name: Janus kinase and microtubule interacting protein 3 (Neuroendocrine long coiled coil protein 2)

Length: 844 Mass: 98529

Tissue specificity: Specifically expressed in the CNS and endocrine tissues. Also detected in other tissues including heart, testis and prostate. {ECO

Sequence

MSKRGMSSRAKGDKAEALAALQAANEDLRAKLTDIQIELQQEKSKVSKVEREKNQELRQVREHEQHKTAVLLTEL
KTKLHEEKMKELQAVRETLLRQHEAELLRVIKIKDNENQRLQALLSALRDGGPEKVKTVLLSEAKEEAKKGFEVE
KVKMQQEISELKGAKRQVEEALTLVIQADKIKAAEIRSVYHLHQEEITRIKKECEREIRRLMEEIKFKDRAVFVL
ERELGVQAGHAQRLQLQKEALDEQLSQVREADRHPGSPRRELPHAAGAGDASDHSGSPEQQLDEKDARRFQLKIA
ELSAIIRKLEDRNALLSEERNELLKRVREAESQYKPLLDKNKRLSRKNEDLSHALRRMENKLKFVTQENIEMRQR
AGIIRRPSSLNDLDQSQDEREVDFLKLQIVEQQNLIDELSKTLETAGYVKSVLERDKLLRFRKQRKKMAKLPKPV
VVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLEEGMAKEETELRFRQLTMEYQALQRAYALLQEQVGG
TLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMKWIEEKQALYRRNQELVEKIKQMETEEARLRHEVQD
ARDQNELLEFRILELEERERKSPAISFHHTPFVDGKSPLQVYCEAEGVTDIVVAELMKKLDILGDNANLTNEEQV
VVIQARTVLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHILELEAMLYDA
LQQEAGAKVAELLSEEEREKLKVAVEQWKRQVMSELRERDAQILRERMELLQLAQQRIKELEERIEAQKRQIKEL
EEKFLFLFLFFSLAFILWS

Structural information

Interpro:	IPR024836 IPR031994
STRING:	ENSP00000298622

Other Databases

GeneCards: JAKMIP3 Malacards: JAKMIP3

Gene ontology

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GO accession	Term name	Evidence code	Go category
GO:0008017	microtubule binding	IEA	molecular function
GO:0019900	kinase binding	IEA	molecular function
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0005794	Golgi apparatus	IEA	cellular component

Diseases

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Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

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PMID	Condition	Population details	Infertility_type	Associated_genes	Abstract
17327269	Teratozoos permia	19 (6 controls , 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)	Show abstract
28606200	Cryptorchi dism	Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
28606200	Cryptorchi dism	Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
28606200	Cryptorchi dism	Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract
25753583	Unexplaine d infertil ity	46 (17 fertile men, 29 male pa tients)	Male infertility	Microarray	Show abstract

Male Infertility knowledgebase

A repository with genes crucial for male fertility

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Gene Summary

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Gene ontology

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Diseases

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PubMed references

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Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

Protein Summary

Gene ontology

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Diseases Expand All | Collapse All

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PubMed references

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Diseases

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