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Gene id 2734
Gene Summary    Protein Summary    Gene ontology    KEGG pathways    Diseases    PubMed    

Gene Summary

Gene Symbol GLG1   Gene   UCSC   Ensembl
Aliases CFR-1, ESL-1, MG-160, MG160
Gene name golgi glycoprotein 1
Alternate names Golgi apparatus protein 1, E-selectin ligand 1, cysteine-rich fibroblast growth factor receptor, golgi sialoglycoprotein MG-160,
Gene location 16q23.1 (74607113: 74447439)     Exons: 27     NC_000016.10
OMIM 600753

Protein Summary

Protein general information Q92896  

Name: Golgi apparatus protein 1 (CFR 1) (Cysteine rich fibroblast growth factor receptor) (E selectin ligand 1) (ESL 1) (Golgi sialoglycoprotein MG 160)

Length: 1179  Mass: 134552

Tissue specificity: Widely expressed. Highest levels in pancreas, skeletal muscle, placenta, heart, testis and ovary. Also found in the kidney, liver, lung and brain. {ECO

Sequence MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQ
QQQQQQQQQPQPPQPPFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENE
ISSDCNHLLWNYKLNLTTDPKFESVAREVCKSTITEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTA
IIFSDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEREPKIQVSELCKKAILRVAE
LSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLIAQDYKVSYSLAKS
CKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEH
HCSGLHRKGRTLHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMI
LSCLMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSEFMPQGAVFSCLYRHA
YRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLVVECRDIV
GNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFR
FSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRRQLRVEELEMTEDIRLEPDLYEA
CKSDIKNFCSAVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTM
LQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPMLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRY
ADQRLSSDCEDQIRIIIQESALDYRLDPQLQLHCSDEISSLCAEEAAAQEQTGQVEECLKVNLLKIKTELCKKEV
LNMLKESKADIFVDPVLHTACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKV
APADGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR
Structural information
Interpro:  IPR001893  IPR017873  IPR039728  
Prosite:   PS51289

DIP:  

27582

MINT:  
STRING:   ENSP00000205061
Other Databases GeneCards:  GLG1  Malacards:  GLG1

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0017134 fibroblast growth factor
binding
IBA molecular function
GO:0000139 Golgi membrane
IBA cellular component
GO:0000139 Golgi membrane
IEA cellular component
GO:0016020 membrane
IEA cellular component
GO:0030054 cell junction
IEA cellular component
GO:0005794 Golgi apparatus
IEA cellular component
GO:0005856 cytoskeleton
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0045202 synapse
IEA cellular component
GO:0005737 cytoplasm
IEA cellular component
GO:0016020 membrane
IEA cellular component
GO:0005102 signaling receptor bindin
g
TAS molecular function
GO:0000139 Golgi membrane
TAS cellular component
GO:0005886 plasma membrane
TAS cellular component
GO:0050900 leukocyte migration
TAS biological process
GO:0060349 bone morphogenesis
IEA biological process
GO:0030512 negative regulation of tr
ansforming growth factor
beta receptor signaling p
athway
IEA biological process
GO:0010955 negative regulation of pr
otein processing
IEA biological process
GO:0032330 regulation of chondrocyte
differentiation
IEA biological process
GO:0031012 extracellular matrix
IEA cellular component
GO:0005794 Golgi apparatus
IEA cellular component
GO:0000139 Golgi membrane
IEA cellular component
GO:0150051 postsynaptic Golgi appara
tus
IEA cellular component
GO:0000139 Golgi membrane
IEA cellular component
GO:0005856 cytoskeleton
IEA cellular component
GO:0005794 Golgi apparatus
IDA cellular component
GO:0016020 membrane
HDA cellular component
GO:0070062 extracellular exosome
HDA cellular component
GO:0070062 extracellular exosome
HDA cellular component

KEGG pathways

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Pathway idPathway name
hsa04514Cell adhesion molecules
Associated diseases References
Cryptorchidism MIK: 28606200
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract