Gene id |
2734 |
Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
Gene Symbol |
GLG1 Gene UCSC Ensembl |
Aliases |
CFR-1, ESL-1, MG-160, MG160 |
Gene name |
golgi glycoprotein 1 |
Alternate names |
Golgi apparatus protein 1, E-selectin ligand 1, cysteine-rich fibroblast growth factor receptor, golgi sialoglycoprotein MG-160, |
Gene location |
16q23.1 (74607113: 74447439) Exons: 27 NC_000016.10
|
OMIM |
600753 |
Protein Summary
|
Protein general information
| Q92896
Name: Golgi apparatus protein 1 (CFR 1) (Cysteine rich fibroblast growth factor receptor) (E selectin ligand 1) (ESL 1) (Golgi sialoglycoprotein MG 160)
Length: 1179 Mass: 134552
Tissue specificity: Widely expressed. Highest levels in pancreas, skeletal muscle, placenta, heart, testis and ovary. Also found in the kidney, liver, lung and brain. {ECO
|
Sequence |
MAACGRVRRMFRLSAALHLLLLFAAGAEKLPGQGVHSQGQGPGANFVSFVGQAGGGGPAGQQLPQLPQSSQLQQQ QQQQQQQQQPQPPQPPFPAGGPPARRGGAGAGGGWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENE ISSDCNHLLWNYKLNLTTDPKFESVAREVCKSTITEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTA IIFSDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEREPKIQVSELCKKAILRVAE LSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMSEKCREALTTRQKLIAQDYKVSYSLAKS CKSDLKKYRCNVENLPRSREARLSYLLMCLESAVHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEH HCSGLHRKGRTLHCLMKVVRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMI LSCLMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSEFMPQGAVFSCLYRHA YRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCSEKTETGQELECLQDHLDDLVVECRDIV GNLTELESEDIQIEALLMRACEPIIQNFCHDVADNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFR FSYKFKMACKEDVLKLCPNIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRRQLRVEELEMTEDIRLEPDLYEA CKSDIKNFCSAVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMIKRFCPEADSKTM LQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPMLRKACKADIPKFCHGILTKAKDDSELEGQVISCLKLRY ADQRLSSDCEDQIRIIIQESALDYRLDPQLQLHCSDEISSLCAEEAAAQEQTGQVEECLKVNLLKIKTELCKKEV LNMLKESKADIFVDPVLHTACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKV APADGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR
|
Structural information |
|
Other Databases |
GeneCards: GLG1  Malacards: GLG1 |
|
GO accession | Term name | Evidence code | Go category |
---|
GO:0017134 |
fibroblast growth factor binding
|
IBA |
molecular function |
GO:0000139 |
Golgi membrane
|
IBA |
cellular component |
GO:0000139 |
Golgi membrane
|
IEA |
cellular component |
GO:0016020 |
membrane
|
IEA |
cellular component |
GO:0030054 |
cell junction
|
IEA |
cellular component |
GO:0005794 |
Golgi apparatus
|
IEA |
cellular component |
GO:0005856 |
cytoskeleton
|
IEA |
cellular component |
GO:0016021 |
integral component of mem brane
|
IEA |
cellular component |
GO:0045202 |
synapse
|
IEA |
cellular component |
GO:0005737 |
cytoplasm
|
IEA |
cellular component |
GO:0016020 |
membrane
|
IEA |
cellular component |
GO:0005102 |
signaling receptor bindin g
|
TAS |
molecular function |
GO:0000139 |
Golgi membrane
|
TAS |
cellular component |
GO:0005886 |
plasma membrane
|
TAS |
cellular component |
GO:0050900 |
leukocyte migration
|
TAS |
biological process |
GO:0060349 |
bone morphogenesis
|
IEA |
biological process |
GO:0030512 |
negative regulation of tr ansforming growth factor beta receptor signaling p athway
|
IEA |
biological process |
GO:0010955 |
negative regulation of pr otein processing
|
IEA |
biological process |
GO:0032330 |
regulation of chondrocyte differentiation
|
IEA |
biological process |
GO:0031012 |
extracellular matrix
|
IEA |
cellular component |
GO:0005794 |
Golgi apparatus
|
IEA |
cellular component |
GO:0000139 |
Golgi membrane
|
IEA |
cellular component |
GO:0150051 |
postsynaptic Golgi appara tus
|
IEA |
cellular component |
GO:0000139 |
Golgi membrane
|
IEA |
cellular component |
GO:0005856 |
cytoskeleton
|
IEA |
cellular component |
GO:0005794 |
Golgi apparatus
|
IDA |
cellular component |
GO:0016020 |
membrane
|
HDA |
cellular component |
GO:0070062 |
extracellular exosome
|
HDA |
cellular component |
GO:0070062 |
extracellular exosome
|
HDA |
cellular component |
|
|
Pathway id | Pathway name |
hsa04514 | Cell adhesion molecules | |
|
Associated diseases |
References |
Cryptorchidism | MIK: 28606200 |
Teratozoospermia | MIK: 17327269 |
|
|
PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
17327269 |
Teratozoos permia
|
|
|
19 (6 controls , 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
28606200 |
Cryptorchi dism
|
|
|
Monozgotic twin s (1 control, I cwith cryptorc hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
28606200 |
Cryptorchi dism
|
|
|
Monozgotic twin s (1 control, I cwith cryptorc hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
28606200 |
Cryptorchi dism
|
|
|
Monozgotic twin s (1 control, I cwith cryptorc hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
28606200 |
Cryptorchi dism
|
|
|
Monozgotic twin s (1 control, I cwith cryptorc hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
28606200 |
Cryptorchi dism
|
|
|
Monozgotic twin s (1 control, I cwith cryptorc hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
28606200 |
Cryptorchi dism
|
|
|
Monozgotic twin s (1 control, I cwith cryptorc hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|