• Gene id: 27254

Gene Summary

• Gene Symbol: CSDC2   Gene   UCSC   Ensembl
• Aliases: PIPPIN, dJ347H13.2
• Gene name: cold shock domain containing C2
• Alternate names: cold shock domain-containing protein C2, RNA-binding protein pippin, cold shock domain containing C2, RNA binding,
• Gene location: 22q13.2 (41561009: 41576665)     Exons: 4     NC_000022.11
• OMIM: 617518

Protein Summary

• Protein general information: Q9Y534  
  • Name: Cold shock domain containing protein C2 (RNA binding protein PIPPin)
  • Length: 153  
  • Mass: 16786
• Sequence:

  MTSESTSPPVVPPLHSPKSPVWPTFPFHREGSRVWERGGVPPRDLPSPLPTKRTRTYSATARASAGPVFKGVCKQ
  FSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIPPKNQKFQAVEVVLTQLAPHTPHETWSGQV
  VGS

• Structural information:
  • Protein Domains: (68..13-)
    (/note="CSD"-)
  • Interpro: IPR011129  IPR019844  IPR002059  IPR012340  
  • Prosite: PS00352 PS51857
  • CDD: cd04458
  • STRING: ENSP00000302485
• Other Databases: GeneCards:  CSDC2  Malacards:  CSDC2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0043488	regulation of mRNA stability	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component
GO:0003730	mRNA 3'-UTR binding	IBA	molecular function
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0003723	RNA binding	IEA	molecular function
GO:0006397	mRNA processing	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0003723	RNA binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0008134	transcription factor binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0003723	RNA binding	NAS	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq