• Gene id: 27120

Gene Summary

• Gene Symbol: DKKL1   Gene   UCSC   Ensembl
• Aliases: CT34, SGY, SGY-1, SGY1
• Gene name: dickkopf like acrosomal protein 1
• Alternate names: dickkopf-like protein 1, cancer/testis antigen 34, dickkopf-like 1, protein soggy-1, soggy, soggy-1, testicular secretory protein Li 15,
• Gene location: 19q13.33 (49360519: 49375131)     Exons: 10     NC_000014.9
• Gene summary(Entrez): The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple altern
• OMIM: 605418

Diseases

Associated diseases	References
Multiple sclerosis	GAD: 21833088
Asthenozoospermia	MIK: 29643039
May be involved in acrosome assembly or function	MIK: 15892050
Male factor infertility	MIK: 29643039
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Asthenospermia	MIK: 29643039
Male infertility	MIK: 29643039
Hypospermatogenesis	MIK: 28361989
May be involved in acrosome assembly or function	MIK: 15892050
Non obstructive azoospermia	MIK: 24012201
Sertoli cell only syndrome	MIK: 23869807

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
15892050	May be involved in acrosome assembly or function				Male infertility
29643039	Asthenospermia, Male infertility				Male infertility
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray