|
Gene id |
26528 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
DAZAP1 Gene UCSC Ensembl |
|
Gene name |
DAZ associated protein 1 |
|
Alternate names |
DAZ-associated protein 1, deleted in azoospermia-associated protein 1, testicular tissue protein Li 50, |
|
Gene location |
19p13.3 (1407585: 1435683) Exons: 16 NC_000009.12
|
|
Gene summary(Entrez) |
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster map
|
|
OMIM |
607430 |
|
| Pathway id | Pathway name |
|---|
| hsa03015 | mRNA surveillance pathway | |
|
| Associated diseases |
References |
| Male factor infertility | MIK: 23658607 |
| Associated with spermatogenesis | MIK: 18669443 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 18669443 |
Assocaited
with sper
matogenesi
s
|
|
|
|
Male infertility |
|
Show abstract |
| 23658607 |
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|