• Gene id: 26266

Gene Summary

• Gene Symbol: SLC13A4   Gene   UCSC   Ensembl
• Aliases: NAS2, SUT-1, SUT1
• Gene name: solute carrier family 13 member 4
• Alternate names: solute carrier family 13 member 4, Na(+)/sulfate cotransporter SUT-1, solute carrier family 13 (sodium/sulfate symporter), member 4, solute carrier family 13 (sodium/sulfate symporters), member 4, solute carrier family 13 (sodium/sulphate symporters), member ,
• Gene location: 7q33 (20684559: 20701215)     Exons: 4     NC_000014.9
• OMIM: 604309

Protein Summary

• Protein general information: Q9UKG4  
  • Name: Solute carrier family 13 member 4 (Na(+)/sulfate cotransporter SUT 1) (NaS2)
  • Length: 626  
  • Mass: 69358
  • Tissue specificity: Highly expressed in placenta and testis with intermediate levels in brain and lower levels in heart, thymus and liver. {ECO
• Sequence:

  MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSN
  EVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPI
  VEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTA
  NQHQGKKQHPSQEKPQVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQ
  YPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYP
  EMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKNDGENQEHSLGTE
  PIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATI
  TIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAI
  NTWGVSLFHLDTYPAWARVSNITDQA

• Structural information:
  • Interpro: IPR001898  
  • STRING: ENSP00000297282
• Other Databases: GeneCards:  SLC13A4  Malacards:  SLC13A4

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881