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Gene id 26157
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol GIMAP2   Gene   UCSC   Ensembl
Aliases HIMAP2, IAN12, IMAP2
Gene name GTPase, IMAP family member 2
Alternate names GTPase IMAP family member 2, immune-associated nucleotide-binding protein 12, immunity associated protein 2,
Gene location 7q36.1 (150685705: 150693640)     Exons: 3     NC_000007.14
Gene summary(Entrez) This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 20

Protein Summary

Protein general information Q9UG22  

Name: GTPase IMAP family member 2 (Immunity associated protein 2) (hIMAP2)

Length: 337  Mass: 38017

Tissue specificity: Detected in T-cells. {ECO

Sequence MDQNEHSHWGPHAKGQCASRSELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGNREIVI
IDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTSQDQQAAQRVKEIFGEDAMGHTIVLFTHKED
LNGGSLMDYMHDSDNKALSKLVAACGGRICAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYSLIQRS
KCGPVGSDERVKEFKQSLIKYMETQRSYTALAEANCLKGALIKTQLCVLFCIQLFLRLIILWLCILHSMCNLFCC
LLFSMCNLFCSLLFIIPKKLMIFLRTVIRLERKTPRL
Structural information
Protein Domains
(20..22-)
(/note="AIG1-type-G")
Interpro:  IPR006703  IPR027417  
Prosite:   PS51720

PDB:  
2XTM 2XTN 2XTO 2XTP 3P1J
PDBsum:   2XTM 2XTN 2XTO 2XTP 3P1J

DIP:  

59483

STRING:   ENSP00000223293
Other Databases GeneCards:  GIMAP2  Malacards:  GIMAP2

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0005783 endoplasmic reticulum
IBA cellular component
GO:0005811 lipid droplet
IDA cellular component
GO:0005525 GTP binding
IEA molecular function
GO:0005811 lipid droplet
IEA cellular component
GO:0005525 GTP binding
IEA molecular function
GO:0000166 nucleotide binding
IEA molecular function
GO:0042802 identical protein binding
IPI molecular function
GO:0005515 protein binding
IPI molecular function
GO:0005811 lipid droplet
IEA cellular component
Associated diseases References
Aberrant CpGs in Low Motility Sperm MIK: 21674046

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract