Male Infertility Database

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Gene id

25900

Gene Summary Protein Summary Gene ontology Diseases PubMed

Gene Summary

Gene Symbol

IFFO1 Gene UCSC Ensembl

Aliases

HOM-TES-103, IFFO

Gene name

intermediate filament family orphan 1

Alternate names

intermediate filament family orphan 1, intermediate filament-like MGC:2625,

Gene location

12p13.31 (6556096: 6538960) Exons: 13 NC_000012.12

Gene summary(Entrez)

This gene is a member of the intermediate filament family. Intermediate filaments are proteins which are primordial components of the cytoskeleton and nuclear envelope. The proteins encoded by the members of this gene family are evolutionarily and structu

OMIM

618040

Protein Summary

Protein general information

Q0D2I5

Name: Intermediate filament family orphan 1 (Tumor antigen HOM TES 103)

Length: 559 Mass: 61979

Tissue specificity: Ubiquitously expressed. {ECO

Sequence

MNPLFGPNLFLLQQEQQGLAGPLGDSLGGDHFAGGGDLPPAPLSPAGPAAYSPPGPGPAPPAAMALRNDLGSNIN
VLKTLNLRFRCFLAKVHELERRNRLLEKQLQQALEEGKQGRRGLGRRDQAVQTGFVSPIRPLGLQLGARPAAVCS
PSARVLGSPARSPAGPLAPSAASLSSSSTSTSTTYSSSARFMPGTIWSFSHARRLGPGLEPTLVQGPGLSWVHPD
GVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEEYTVRIQLQDRVNELQEEAQEADACQEELALKVEQLKAE
LVVFKGLMSNNLSELDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNCEDMIQMFQVPSMGGRKRERKAAVEED
TSLSESEGPRQPDGDEEESTALSINEEMQRMLNQLREYDFEDDCDSLTWEETEETLLLWEDFSGYAMAAAEAQGE
QEDSLEKVIKDTESLFKTREKEYQETIDQIELELATAKNDMNRHLHEYMEMCSMKRGLDVQMETCRRLITQSGDR
KSPAFTAVPLSDPPPPPSEAEDSDRDVSSDSSMR

Structural information

Protein Domains	(73..52-) (/note="IF-rod) (/evidence="ECO:0000255\|PROSITE-ProRule:PRU01188"-)
Interpro:	IPR039008 IPR042180
Prosite:	PS51842
PDB:	6ABO
PDBsum:	6ABO
STRING:	ENSP00000482285

Other Databases

GeneCards: IFFO1 Malacards: IFFO1

Gene ontology

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GO accession	Term name	Evidence code	Go category
GO:0005882	intermediate filament	IEA	cellular component

Diseases

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Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

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PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes	Abstract
28606200	Cryptorchi dism			Monozgotic twin s (1 control, I cwith cryptorc hidism)	Male infertility	MeDIP-Seq	Show abstract

Male Infertility knowledgebase

A repository with genes crucial for male fertility

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Male Infertility knowledgebase

A repository with genes crucial for male fertility

Search Result

Gene Summary

Protein Summary

Gene ontology

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Diseases Expand All | Collapse All

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PubMed references

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Diseases

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