• Gene id: 25880

Gene Summary

• Gene Symbol: TMEM186   Gene   UCSC   Ensembl
• Aliases: C16orf51
• Gene name: transmembrane protein 186
• Alternate names: transmembrane protein 186,
• Gene location: 16p13.2 (8797638: 8795179)     Exons: 2     NC_000016.10
• Gene summary(Entrez): This gene encodes a potential transmembrane protein. [provided by RefSeq, Dec 2012]
• OMIM: 611159

Protein Summary

• Protein general information: Q96B77  
  • Name: Transmembrane protein 186
  • Length: 213  
  • Mass: 24893
• Sequence:

  MAALLRAVRRFRGKAVWERPLHGLWCCSGQEDPKRWVGSSSPISKEKLPNAETEKFWMFYRFDAIRTFGFLSRLK
  LAQTALTVVALPPGYYLYSQGLLTLNTVCLMSGISGFALTMLCWMSYFLRRLVGILYLNESGTMLRVAHLNFWGW
  RQDTYCPMADVIPLTETKDRPQEMFVRIQRYSGKQTFYVTLRYGRILDRERFTQVFGVHQMLK

• Structural information:
  • Interpro: IPR026571  
  • STRING: ENSP00000331640
• Other Databases: GeneCards:  TMEM186  Malacards:  TMEM186

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005739	mitochondrion	IBA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005739	mitochondrion	IDA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881