• Gene id: 25873

Gene Summary

• Gene Symbol: RPL36   Gene   UCSC   Ensembl
• Aliases: L36
• Gene name: ribosomal protein L36
• Alternate names: 60S ribosomal protein L36, large ribosomal subunit protein eL36,
• Gene location: 19p13.3 (5690294: 5691874)     Exons: 18     NC_000019.10
• Gene summary(Entrez): Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal pro
• OMIM: 617893

Protein Summary

• Protein general information: Q9Y3U8  
  • Name: 60S ribosomal protein L36 (Large ribosomal subunit protein eL36)
  • Length: 105  
  • Mass: 12254
• Sequence:

  MALRYPMAVGLNKGHKVTKNVSKPRHSRRRGRLTKHTKFVRDMIREVCGFAPYERRAMELLKVSKDKRALKFIKK
  RVGTHIRAKRKREELSNVLAAMRKAAAKKD

• Structural information:
  • Interpro: IPR038097  IPR000509  
  • Prosite: PS01190
  • PDB: 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
  • PDBsum: 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
  • STRING: ENSP00000464342
• Other Databases: GeneCards:  RPL36  Malacards:  RPL36

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0002181	cytoplasmic translation	IBA	biological process
GO:0022625	cytosolic large ribosomal subunit	IBA	cellular component
GO:0003735	structural constituent of ribosome	IBA	molecular function
GO:0022625	cytosolic large ribosomal subunit	IDA	cellular component
GO:0002181	cytoplasmic translation	IDA	biological process
GO:0042788	polysomal ribosome	IDA	cellular component
GO:0005840	ribosome	IEA	cellular component
GO:0006412	translation	IEA	biological process
GO:0003735	structural constituent of ribosome	IEA	molecular function
GO:0005840	ribosome	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0006413	translational initiation	TAS	biological process
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	TAS	biological process
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	TAS	biological process
GO:0019083	viral transcription	TAS	biological process
GO:0005730	nucleolus	IDA	cellular component
GO:0005829	cytosol	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0022625	cytosolic large ribosomal subunit	HDA	cellular component
GO:0006412	translation	NAS	biological process
GO:0003723	RNA binding	HDA	molecular function
GO:0016020	membrane	HDA	cellular component
GO:0003735	structural constituent of ribosome	NAS	molecular function
GO:0005730	nucleolus	HDA	cellular component
GO:0005737	cytoplasm	HDA	cellular component

KEGG pathways

Pathway id	Pathway name
hsa03010	Ribosome

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)