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Gene id |
2534 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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Gene Symbol |
FYN Gene UCSC Ensembl |
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Aliases |
SLK, SYN, p59-FYN |
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Gene name |
FYN proto-oncogene, Src family tyrosine kinase |
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Alternate names |
tyrosine-protein kinase Fyn, FYN oncogene related to SRC, FGR, YES, OKT3-induced calcium influx regulator, c-syn protooncogene, proto-oncogene Syn, proto-oncogene c-Fyn, src-like kinase, src/yes-related novel, tyrosine kinase p59fyn(T), |
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Gene location |
6q21 (111873451: 111660331) Exons: 19 NC_000006.12
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Gene summary(Entrez) |
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and
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OMIM |
137025 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Arterial hypertension | GAD: 17334644 |
| Cleft defects | GAD: 18978678 |
| Alzheimer's disease | GAD: 15082191 |
| Parkinson disease | GAD: 18628988 |
| Bipolar disorder | GAD: 19330793 |
| Schizophrenia | GAD: 11121167 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Plays a role in spermatogenesis and development of testicular germ cells | MIK: 11944913 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 11944913 |
Plays a ro
le in sper
matogenesi
s and deve
lopment of
testicula
r germ cel
ls
|
|
|
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Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
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19 (6 controls
, 13 cases)
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Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
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|
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18
|
Male infertility |
GSE26881
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Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
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46 (17 fertile
men, 29 male pa
tients)
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Male infertility |
Microarray
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Show abstract |
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