|
Gene id |
23627 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
PRND Gene UCSC Ensembl |
|
Aliases |
DOPPEL, DPL, PrPLP, dJ1068H6.4 |
|
Gene name |
prion like protein doppel |
|
Alternate names |
prion-like protein doppel, downstream prion protein-like, prion gene complex, downstream, prion protein 2 (dublet), |
|
Gene location |
20p13 (4721908: 4728459) Exons: 2 NC_000015.10
|
|
Gene summary(Entrez) |
This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored g
|
|
OMIM |
604263 |
|
| Associated diseases |
References |
| Alzheimer's disease | GAD: 14745079 |
| Jakob-Creutzfeldt disease | GAD: 14970845 |
| Role in male fertility by controlling several aspects of male gametogenesis and sperm-egg interaction | MIK: 12110578 |
| Hypospermatogenesis | MIK: 28361989 |
| Role in male fertility by controlling several aspects of male gametogenesis and sperm-egg interaction | MIK: 12110578 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 12110578 |
Role in ma
le fertili
ty by cont
rolling se
veral aspe
cts of mal
e gametoge
nesis and
sperm-egg
interactio
n
|
|
|
|
Male infertility |
|
Show abstract |
| 28361989 |
Hyposperma
togenesis
|
|
|
6 (3 controls,
3 Klienfelter s
yndrome
|
Male infertility |
Microarray
|
Show abstract |
|