• Gene id: 23015

Gene Summary

• Gene Symbol: GOLGA8A   Gene   UCSC   Ensembl
• Aliases: CFAP286, FAP286, GM88, GOLGA8B
• Gene name: golgin A8 family member A
• Alternate names: golgin subfamily A member 8A, 88 kDa Golgi matrix protein, 88-kDa golgi protein, GM88 autoantigen, Golgin subfamily A member 8B, golgi autoantigen, golgin subfamily a, 8A, golgin-67,
• Gene location: 15q14 (34437807: 34379067)     Exons: 24     NC_000015.10
• Gene summary(Entrez): The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked, flattened membrane sacs referred to as cisternae. Interactions between the Golgi and microtubules are
• OMIM: 616180

Protein Summary

• Protein general information: A7E2F4  
  • Name: Golgin subfamily A member 8A (88 kDa Golgi matrix protein) (GM88) (GM88 autoantigen)
  • Length: 631  
  • Mass: 70117
• Sequence:

  MLPVDGEERKSEGSDTEGDRTSPCAVSSATLKDLEVGGSGRRCSDPAGQPSNLLPQRGLGAPLPAETAHTQPSPN
  DRSLYLSPKSSSASSSLHARQSPCQEQAAVLNSRSIKISRLNDTIKSLKQQKKQVEHQLEEEKKANNEKQKAERE
  LEGQIQRLNTEKKKLNTDLYHMKHSLRYFEEESKDLAGRLQRSSQRIGELEWSLCAVAATQKKKPDGFSSRSKAL
  LKRQLEQSIREQILLKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEEL
  ERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQKERLREQEERLQEQQE
  RLREREKRLQQLAEPQSDLEELKHENKSALQLEQQVKELQEKLGQVMETLTSAEKEPEAAVPASGTGGESSGLMD
  LLEEKADLREHVEKLELGFIQYRRERCHQKVHRLLTEPGDSAKDASPGGGHHQAGPGQGGEEGEAAGAAGDGVAA
  CGSYSEGHGKFLAAARNPAAEPSPGAPAPQELGAADKHGDLCEASLTNSVEPAQGEAREGSSQDNPTAQPVVQLL
  GEMQDHQEHPGLGSNCCVPCFCWAWLPRRRR

• Structural information:
  • Interpro: IPR024858  
  • STRING: ENSP00000352111
• Other Databases: GeneCards:  GOLGA8A  Malacards:  GOLGA8A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005794	Golgi apparatus	IBA	cellular component
GO:0005801	cis-Golgi network	IBA	cellular component
GO:0000137	Golgi cis cisterna	IBA	cellular component
GO:0007030	Golgi organization	IBA	biological process
GO:0032580	Golgi cisterna membrane	IBA	cellular component
GO:0051225	spindle assembly	IBA	NOT|biological process
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0005794	Golgi apparatus	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0032580	Golgi cisterna membrane	IEA	cellular component
GO:0005794	Golgi apparatus	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R