• Gene id: 22879

Gene Summary

• Gene Symbol: MON1B   Gene   UCSC   Ensembl
• Aliases: HSRG1, SAND2, SRG1
• Gene name: MON1 homolog B, secretory trafficking associated
• Alternate names: vacuolar fusion protein MON1 homolog B, HSV-1 stimulation-related gene 1 protein, HSV-I stimulating-related protein, MON1 secretory trafficking family member B,
• Gene location: 16q23.1 (77191189: 77202397)     Exons: 6     NC_000016.10
• OMIM: 0

Protein Summary

• Protein general information: Q7L1V2  
  • Name: Vacuolar fusion protein MON1 homolog B (HSV 1 stimulation related gene 1 protein) (HSV I stimulating related protein)
  • Length: 547  
  • Mass: 59217
• Sequence:

  MEVGGDTAAPAPGGAEDLEDTQFPSEEAREGGGVHAVPPDPEDEGLEETGSKDKDQPPSPSPPPQSEALSSTSRL
  WSPAAPENSPTCSPESSSGGQGGDPSDEEWRSQRKHVFVLSEAGKPIYSRYGSVEALSATMGVMTALVSFVQSAG
  DAIRAIYAEDHKLVFLQQGPLLLVAMSRTSQSAAQLRGELLAVHAQIVSTLTRASVARIFAHKQNYDLRRLLAGS
  ERTLDRLLDSMEQDPGALLLGAVRCVPLARPLRDALGALLRRCTAPGLALSVLAVGGRLITAAQERNVLAECRLD
  PADLQLLLDWVGAPAFAAGEAWAPVCLPRFNPDGFFYAYVARLDAMPVCLLLLGTQREAFHAMAACRRLVEDGMH
  ALGAMRALGEAASFSNASSASAPAYSVQAVGAPGLRHFLYKPLDIPDHHRQLPQFTSPELEAPYSREEERQRLSD
  LYHRLHARLHSTSRPLRLIYHVAEKETLLAWVTSKFELYTCLSPLVTKAGAILVVTKLLRWVKKEEDRLFIRYPP
  KYSTPPATSTDQAAHNGLFTGL

• Structural information:
  • Interpro: IPR004353  
  • STRING: ENSP00000248248
• Other Databases: GeneCards:  MON1B  Malacards:  MON1B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0019085	early viral transcription	IDA	biological process
GO:0035658	Mon1-Ccz1 complex	IDA	cellular component
GO:0019086	late viral transcription	IDA	biological process
GO:0005737	cytoplasm	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0006623	protein targeting to vacuole	IEA	biological process
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881