• Gene id: 22809

Gene Summary

• Gene Symbol: ATF5   Gene   UCSC   Ensembl
• Aliases: ATFX, HMFN0395
• Gene name: activating transcription factor 5
• Alternate names: cyclic AMP-dependent transcription factor ATF-5, cAMP-dependent transcription factor ATF-5, transcription factor ATFx,
• Gene location: 19q13.33 (79078293: 78934418)     Exons: 42     NC_000006.12
• OMIM: 606398

Protein Summary

• Protein general information: Q9Y2D1  
  • Name: Cyclic AMP dependent transcription factor ATF 5 (cAMP dependent transcription factor ATF 5) (Activating transcription factor 5) (Transcription factor ATFx)
  • Length: 282  
  • Mass: 30674
  • Tissue specificity: Widely expressed with higher expression levels in liver. {ECO
• Sequence:

  MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTA
  LLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDL
  PQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRY
  RQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC

• Structural information:
  • Protein Domains: (208..27-)
    (/note="bZIP-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00978"-)
  • Interpro: IPR029855  IPR004827  
  • Prosite: PS50217
  • STRING: ENSP00000396954
• Other Databases: GeneCards:  ATF5  Malacards:  ATF5

Gene ontology

GO accession	Term name	Evidence code	Go category

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881