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Gene id 222256
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol CDHR3   Gene   UCSC   Ensembl
Aliases CDH28
Gene name cadherin related family member 3
Alternate names cadherin-related family member 3, cadherin-like protein 28,
Gene location 7q22.3 (105876749: 106036431)     Exons: 24     NC_000007.14
OMIM 131220

Protein Summary

Protein general information Q6ZTQ4  

Name: Cadherin related family member 3 (Cadherin like protein 28)

Length: 885  Mass: 97977

Tissue specificity: Expressed in bronchial epithelium from adults and in fetal lung tissue. {ECO

Sequence MQEAIILLALLGAMSGGEALHLILLPATGNVAENSPPGTSVHKFSVKLSASLSPVIPGFPQIVNSNPLTEAFRVN
WLSGTYFEVVTTGMEQLDFETGPNIFDLQIYVKDEVGVTDLQVLTVQVTDVNEPPQFQGNLAEGLHLYIVERANP
GFIYQVEAFDPEDTSRNIPLSYFLISPPKSFRMSANGTLFSTTELDFEAGHRSFHLIVEVRDSGGLKASTELQVN
IVNLNDEVPRFTSPTRVYTVLEELSPGTIVANITAEDPDDEGFPSHLLYSITTVSKYFMINQLTGTIQVAQRIDR
DAGELRQNPTISLEVLVKDRPYGGQENRIQITFIVEDVNDNPATCQKFTFSIMVPERTAKGTLLLDLNKFCFDDD
SEAPNNRFNFTMPSGVGSGSRFLQDPAGSGKIVLIGDLDYENPSNLAAGNKYTVIIQVQDVAPPYYKNNVYVYIL
TSPENEFPLIFDRPSYVFDVSERRPARTRVGQVRATDKDLPQSSLLYSISTGGASLQYPNVFWINPKTGELQLVT
KVDCETTPIYILRIQATNNEDTSSVTVTVNILEENDEKPICTPNSYFLALPVDLKVGTNIQNFKLTCTDLDSSPR
SFRYSIGPGNVNNHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYKLLVYVTDDNLMSDRKKAEALVETGTVTL
SIKVIPHPTTIITTTPRPRVTYQVLRKNVYSPSAWYVPFVITLGSILLLGLLVYLVVLLAKAIHRHCPCKTGKNK
EPLTKKGETKTAERDVVVETIQMNTIFDGEAIDPVTGETYEFNSKTGARKWKDPLTQMPKWKESSHQGAAPRRVT
AGEGMGSLRSANWEEDELSGKAWAEDAGLGSRNEGGKLGNPKNRNPAFMNRAYPKPHPGK
Structural information
Protein Domains
(23..13-)
(/note="Cadherin-1)
(/evidence="ECO:0000255|PROSITE-ProRule:PRU00043-)
(136..23-)
(/note="Cadherin-2)
(/evidence="ECO:0000255|PROSITE-ProRule:PRU00043-)
(237..34-)
(/note="Cadherin-3)
(/evidence="ECO:0000255|PROSITE-ProRule:-)
Interpro:  IPR039808  IPR002126  IPR015919  
Prosite:   PS50268
STRING:   ENSP00000325954
Other Databases GeneCards:  CDHR3  Malacards:  CDHR3

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0098742 cell-cell adhesion via pl
asma-membrane adhesion mo
lecules
IBA biological process
GO:0045296 cadherin binding
IBA molecular function
GO:0044331 cell-cell adhesion mediat
ed by cadherin
IBA biological process
GO:0043083 synaptic cleft
IBA cellular component
GO:0035249 synaptic transmission, gl
utamatergic
IBA biological process
GO:0034332 adherens junction organiz
ation
IBA biological process
GO:0005912 adherens junction
IBA cellular component
GO:0005509 calcium ion binding
IBA molecular function
GO:0000902 cell morphogenesis
IBA biological process
GO:0043679 axon terminus
IBA cellular component
GO:0016342 catenin complex
IBA cellular component
GO:0016339 calcium-dependent cell-ce
ll adhesion via plasma me
mbrane cell adhesion mole
cules
IBA biological process
GO:0007275 multicellular organism de
velopment
IBA biological process
GO:0007043 cell-cell junction assemb
ly
IBA biological process
GO:0005886 plasma membrane
IDA cellular component
GO:0005509 calcium ion binding
IEA molecular function
GO:0098609 cell-cell adhesion
IEA biological process
GO:0007156 homophilic cell adhesion
via plasma membrane adhes
ion molecules
IEA biological process
GO:0016020 membrane
IEA cellular component
GO:0001618 virus receptor activity
IEA molecular function
GO:0016020 membrane
IEA cellular component
GO:0007155 cell adhesion
IEA biological process
GO:0016032 viral process
IEA biological process
GO:0005886 plasma membrane
IEA cellular component
GO:0016021 integral component of mem
brane
IEA cellular component
GO:0005515 protein binding
IPI molecular function
GO:0005515 protein binding
IPI molecular function
GO:0005515 protein binding
IPI molecular function
GO:0005886 plasma membrane
IEA cellular component
GO:0046718 viral entry into host cel
l
IEA biological process
Associated diseases References
Cryptorchidism MIK: 28606200

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract