• Gene id: 221424

Gene Summary

• Gene Symbol: LRRC73   Gene   UCSC   Ensembl
• Aliases: C6orf154
• Gene name: leucine rich repeat containing 73
• Alternate names: leucine-rich repeat-containing protein 73,
• Gene location: 6p21.1 (43510345: 43506964)     Exons: 6     NC_000006.12

Protein Summary

• Protein general information: Q5JTD7  
  • Name: Leucine rich repeat containing protein 73
  • Length: 316  
  • Mass: 33409
• Sequence:

  MLPSSIQISGEPLSGAEVRDICRGLRDNAVRLLSLRGCRLCDRDFGRICRALAGATSLAQLNLNLGVVSSPSRIK
  QLAEALRTNRSIQSLFLHGSPLTDAGLALLNPALALHPALVALDLGDCMLGDEAINLICGLLPPDGAKSGLKELT
  LSANPGITPKGWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEVLDLEGTGLTNQSAQTLLDMV
  ENYPTALRSLVLAENSISPELQQQICDLLSEGEEEEEVAGGAGDTQEWERGREPAAHQRGSSSWMCPSDPSSQMV
  LMTSGLGDSLLAETEM

• Structural information:
  • Interpro: IPR032675  IPR039984  
  • STRING: ENSP00000361518
• Other Databases: GeneCards:  LRRC73  Malacards:  LRRC73

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Non obstructive azoospermia	MIK: 24012201

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)