• Gene id: 220388

Gene Summary

• Gene Symbol: CCDC89   Gene   UCSC   Ensembl
• Gene name: coiled-coil domain containing 89
• Alternate names: coiled-coil domain-containing protein 89, bc8 orange-interacting protein,
• Gene location: 11q14.1 (18170418: 18223688)     Exons: 11     NC_000008.11

Protein Summary

• Protein general information: Q8N998  
  • Name: Coiled coil domain containing protein 89 (Bc8 orange interacting protein)
  • Length: 374  
  • Mass: 43809
• Sequence:

  MRAPMLQKQQAPRMDTPPPEERLEKQNEKLNNQEEETEFKELDGLREALANLRGLSEEERSEKAMLRSRIEEQSQ
  LICILKRRSDEALERCQILELLNAELEEKMMQEAEKLKAQGEYSRKLEERFMTLAANHELMLRFKDEYKSENIKL
  REENEKLRLENSSLFSQALKDEEAKVLQLTVRCEALTGELETLKERCAQDACQAQAREKELLELQSQQACTHTKE
  TEQLRSQLQTLKQQHQQAVEQIAKAEETHSSLSQELQARLQTVTREKEELLQLSIERGKVLQNKQAEICQLEEKL
  EIANEDRKHALERFEQEAVAVDSNLRVRELQRKVDGIQKAYDELRLQSEAFKKHSLDLLSKERELNGKLRHLSP

• Structural information:
  • STRING: ENSP00000320649
• Other Databases: GeneCards:  CCDC89  Malacards:  CCDC89

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)