• Gene id: 220004

Gene Summary

• Gene Symbol: PPP1R32   Gene   UCSC   Ensembl
• Aliases: C11orf66, IIIG9
• Gene name: protein phosphatase 1 regulatory subunit 32
• Alternate names: protein phosphatase 1 regulatory subunit 32,
• Gene location: 11q12.2 (61481119: 61490927)     Exons: 1     NC_000011.10

Protein Summary

• Protein general information: Q7Z5V6  
  • Name: Protein phosphatase 1 regulatory subunit 32
  • Length: 425  
  • Mass: 47295
• Sequence:

  MMGKLPLGVVSPYVKMSSGGYTDPLKFYATSYCTAYGREDFKPRVGSHVGTGYKSNFQPVVSCQASLEALDNPAR
  GEQAQDHFQSVASQSYRPLEVPDGKHPLPWSMRQTSSGYGREKPSAGPPTKEVRKVHFDTQEHGPQAITGLEPRE
  VPLLHQQQGQDPLERENFRHGPRFMTSEYNSKYLRDPLDQPDFLQKKSIGAKEGSGFTKQSHQSPIVFQPPSQAL
  PGDPALLPGQSVTKSDFLPKTHLHGDEFLPVLARGSKRETAFSRGNERILNPRVPPPCPEPSSVSHQQFQPLHRM
  QQTNVALLGRETVGKKEPTGFSLNNPMYVRSPCDPDRDQRYLTTYNQGYFENIPKGLDQEGWTRGGIQPQMPGGY
  ALSQPVSCMEATPNPMESLRHLHPHVGRTLTSADPFYQNTPHSSRCVAHS

• Structural information:
  • Interpro: IPR031410  
  • STRING: ENSP00000344140
• Other Databases: GeneCards:  PPP1R32  Malacards:  PPP1R32

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0019902	phosphatase binding	IBA	molecular function
GO:0019902	phosphatase binding	IDA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0036064	ciliary basal body	IDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Non obstructive azoospermia	MIK: 24012201
Sertoli cell only syndrome	MIK: 23869807
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq